Worth reading: Opioid Prescribing in the Midst of Crisis – Myths and Realities

https://www.nejm.org/doi/full/10.1056/NEJMp1914257 Great perspective from Michael L. Barnett, M.D., in NEJM. Sadly, it’s paywalled, but I share a useful table from the article below. Barnett describes the current state of opioid prescribing as an over-correction, in which the terrible opioid overdose epidemic has led public health officials and providers to move too far in the opposite…

Worth reading: History in a Crisis — Lessons for Covid-19

Much needed perspective from David S. Jones, M.D., Ph.D., in NEJM. www.nejm.org/doi/full/10.1056/NEJMp2004361 An especially worthwhile excerpt: “History suggests that we are actually at much greater risk of exaggerated fears and misplaced priorities. There are many historical examples of panic about epidemics that never materialized (e.g., H1N1 influenza in 1976, 2006, and 2009). There are countless…

Worth reading: Covid-19 — Navigating the Uncharted

Just published today (February 28, 2020) in the New England Journal of Medicine, from Anthony Fauci and Clifford Lane (director and deputy director, respectively, of the NIH’s National Institute of Allergy & Infectious Disease) and Robert Redfield (director of the CDC). A clear, concise report on what is currently known about the SARS-CoV-2 outbreak from…

Worth reading: A critical view on transgenerational epigenetic inheritance in humans

Abstract “Transgenerational epigenetic inheritance refers to the transmission of epigenetic information through the germline. While it has been observed in plants, nematodes and fruit flies, its occurrence in mammals—and humans in particular—is the matter of controversial debate, mostly because the study of transgenerational epigenetic inheritance is confounded by genetic, ecological and cultural inheritance. In this…